[The linear correlation coefficient of serotonin and prolactin concentrations in plasma of women chronically exposed to carbon disulfide].

A group of 70 women, examined clinically, was divided into two even subgroups: subgroup I--controls, aged 49.8 +/- 3.2 years, non-exposed to carbon disulfide (CS2), and subgroup II, aged 43.6 +/- 1.7 years chronically exposed to CS2 in concentration of 9.36--23.4 mg/m3. The concentration of CS2 was measured using Mc Cammon's method, concentration of serotonin in plasma by employing the colorimetric method according to Manuchin and the radioimmunological method was applied in measuring the prolactin concentration. Student-t test and Pearson's linear correlation coefficient "C" were used for the statistical analysis. It was found that in women exposed to CS2 serotonin and prolactin concentrations were significantly higher (p < 0.001). The linear correlation between serotonin and prolactin concentrations was also significantly positive (r = 0.44; p 0.01) in women expose to carbon disulfide.