International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 1997
Pregnancy-induced hypertension and hyaline membrane disease.
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Carvalho M A, Faúndes A, Santos L C
Аннотация
OBJECTIVES: (1) To determine whether the incidence of hyaline membrane disease (HMD) is different among premature babies of pre-eclamptic women and those of normotensive controls; (2) to determine the relative risk (RR) of HMD according to the severity of pre-eclampsia and gestational age.
METHODS: A retrospective and prospective cohort of 271 pre-eclamptic women and 271 normotensive controls, with gestational age between 28 and 34 weeks was studied, including only singleton pregnancies, live fetuses and well-documented gestational age. Exclusion criteria were ruptured membranes > 24 h, other maternal diseases and previous use of corticosteroids. Statistical analysis included relative risk and multiple logistic regression model.
RESULTS: The RR of HMD for babies of pre-eclamptic women was 0.96 (95% CI: 0.78-1.17), and remained unchanged after controlling for gestational age and multiple logistic regression analysis.
CONCLUSION: Preterm babies of pre-eclamptic mothers had the same probability of having HMD as newborns of normotensive mothers.
METHODS: A retrospective and prospective cohort of 271 pre-eclamptic women and 271 normotensive controls, with gestational age between 28 and 34 weeks was studied, including only singleton pregnancies, live fetuses and well-documented gestational age. Exclusion criteria were ruptured membranes > 24 h, other maternal diseases and previous use of corticosteroids. Statistical analysis included relative risk and multiple logistic regression model.
RESULTS: The RR of HMD for babies of pre-eclamptic women was 0.96 (95% CI: 0.78-1.17), and remained unchanged after controlling for gestational age and multiple logistic regression analysis.
CONCLUSION: Preterm babies of pre-eclamptic mothers had the same probability of having HMD as newborns of normotensive mothers.