Neurobehavior in very preterm infants with low medical risk and full-term infants.

OBJECTIVE

To describe differences in neurobehavior among very preterm infants with low medical risk at term equivalent age and full-term infants.

STUDY

DESIGN

One-hundred eighty-six (136 infants born ≤32 weeks gestation with low medical risk at term equivalent age and 50 full-term infants within 4 days of birth) had standardized neurobehavioral assessments. Low medical risk was defined by ventilation <10 days and absence of significant brain injury, necrotizing enterocolitis, patent ductus arteriosus, and retinopathy of prematurity.

RESULTS

Very preterm infants with low medical risk at term equivalent age demonstrated more sub-optimal reflexes (p < 0.001; ß = 1.53) and more stress (p < 0.001; ß = 0.08) on the NICU Network Neurobehavioral Scale compared to their full-term counterparts. Very preterm infants with low medical risk also performed worse on the Hammersmith Neonatal Neurological Examination (p = 0.005; ß = -3.4).

CONCLUSION

Very preterm infants at term equivalent age continue to demonstrate less optimal neurobehavior compared to full-term infants.