International journal of toxicology · 2026
Safety Assessment of Glycolactones as Used in Cosmetics.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Ferguson Priya, Bergfeld Wilma F, Belsito Donald V, Cohen David E, Klaassen Curtis D, Liebler Daniel C, Peterson Lisa A, Rettie Allan E, Ross David, Shank Ronald C, Slaga Thomas J, Snyder Paul W, Tilton Susan C, Fiume Monice M, Heldreth Bart
Аннотация
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of 5 glycolactone ingredients. Glucoheptonolactone and Gluconolactone are reported to function in cosmetics as skin-conditioning agents-miscellaneous, and Gluconolactone is also reported to function as a chelating agent. No functions are reported for the other 3 ingredients. The Panel considered the available data and concluded that Gluconolactone is safe in cosmetics in the present practices of use and concentration described in this safety assessment; however, the Panel concluded the available data are insufficient to make a determination that Galactonolactone, Glucarolactone, Glucoheptonolactone, and Ribonolactone are safe under the intended conditions of use in cosmetic formulations.