[Mild, moderate and severe dysplasia in exfoliative cytological studies of breast secretions in connection with use of oral contraceptives].

In our present material of 30,000 cytologically investigated mammary secretions we have found since 1980 in 1.55% mild, moderate and severe dysplasias. Due to the high number of women using long time oral contraceptive pills are further investigations necessary. Such women using gestagen accented pills in particular with the gestagen norethisterone acetate are charged with a significant high level of dysplasias in nipple discharge. After stopping or changing the contraceptives, these dysplasias seem to be reversible. These findings should therefore stimulate further intensive examinations, in order to detect in time possible dangerous side effects after long time using of oral contraceptive pills and to avoid them.