Urology · 2026
Metronome Rhythm Based Auditory Stimulation Modulates Pain and Anxiety During Transperineal Prostate Biopsy: A Prospective Clinical Study.
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Öztürk Erdem, Bolat Abdullah, Canbolat Muhammed Zübeyr, Çayırlı Abdullah, Uzel Tuncel, Dağlı İsa
Аннотация
OBJECTIVE: To evaluate whether exposure to different metronome rhythms is associated with variations in patient-reported pain intensity and anxiety levels during transperineal prostate biopsy performed under local anesthesia.
METHODS: This single-center, prospective, non-randomized study included 200 patients undergoing TPBx. Patients were assigned according to routine clinical workflow to a control group or metronome rhythm groups at 60, 80, 100, or 120 bpm. Pain was assessed using the Visual Analog Scale, and anxiety was evaluated using the State-Trait Anxiety Inventory. The primary outcome was overall procedural pain.
RESULTS: Final analysis included 196 patients. Overall pain scores and pain during local anesthetic administration differed significantly among groups (P <.001). The lowest pain scores were observed in the 100 bpm group. Post-procedural anxiety scores were significantly lower in the 60-100 bpm groups compared with the control and 120 bpm groups. Baseline characteristics were comparable.
CONCLUSION: Metronome rhythm-based auditory stimulation was associated with differences in pain and anxiety during TPBx and may represent a simple adjunct to improve patient experience.
METHODS: This single-center, prospective, non-randomized study included 200 patients undergoing TPBx. Patients were assigned according to routine clinical workflow to a control group or metronome rhythm groups at 60, 80, 100, or 120 bpm. Pain was assessed using the Visual Analog Scale, and anxiety was evaluated using the State-Trait Anxiety Inventory. The primary outcome was overall procedural pain.
RESULTS: Final analysis included 196 patients. Overall pain scores and pain during local anesthetic administration differed significantly among groups (P <.001). The lowest pain scores were observed in the 100 bpm group. Post-procedural anxiety scores were significantly lower in the 60-100 bpm groups compared with the control and 120 bpm groups. Baseline characteristics were comparable.
CONCLUSION: Metronome rhythm-based auditory stimulation was associated with differences in pain and anxiety during TPBx and may represent a simple adjunct to improve patient experience.