Targeting Pollutants in the Treatment and Prevention of Atopic Dermatitis.

Mounting evidence suggests atopic dermatitis (AD) is primarily mediated by environmental exposures. This article focuses on specific air pollutants such as isocyanates and those in the benzene, toluene, ethylbenzene, and xylene family. We discuss the current strength and limitations of the data linking air pollution to AD. Brief mention is given to dietary and water-borne factors of concern. The proposed mechanisms of pathology for these chemicals are detailed. Finally, mitigation strategies are discussed with a focus on facilitating discussion between providers and patients related to the ways of improving AD without a prescription.