Scientific reports · 2023
Pulmonary recovery from COVID-19 in patients with metabolic diseases: a longitudinal prospective cohort study.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Sonnweber Thomas, Grubwieser Philipp, Pizzini Alex, Boehm Anna, Sahanic Sabina, Luger Anna, Schwabl Christoph, Widmann Gerlig, Egger Alexander, Hoermann Gregor, Wöll Ewald, Puchner Bernhard, Kaser Susanne, Theurl Igor, Nairz Manfred, Tymoszuk Piotr, Weiss Günter, Joannidis Michael, Löffler-Ragg Judith, Tancevski Ivan
Аннотация
The severity of coronavirus disease 2019 (COVID-19) is related to the presence of comorbidities including metabolic diseases. We herein present data from the longitudinal prospective CovILD trial, and investigate the recovery from COVID-19 in individuals with dysglycemia and dyslipidemia. A total of 145 COVID-19 patients were prospectively followed and a comprehensive clinical, laboratory and imaging assessment was performed at 60, 100, 180, and 360 days after the onset of COVID-19. The severity of acute COVID-19 and outcome at early post-acute follow-up were significantly related to the presence of dysglycemia and dyslipidemia. Still, at long-term follow-up, metabolic disorders were not associated with an adverse pulmonary outcome, as reflected by a good recovery of structural lung abnormalities in both, patients with and without metabolic diseases. To conclude, dyslipidemia and dysglycemia are associated with a more severe course of acute COVID-19 as well as delayed early recovery but do not impair long-term pulmonary recovery.