Internal medicine (Tokyo, Japan) · 2023
Syphilis-related Membranous Nephropathy in a 35-year-old Woman.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Nakayama Yuki, Yamanouchi Masayuki, Mizuno Hiroki, Suwabe Tatsuya, Sekine Akinari, Ikuma Daisuke, Hasegawa Eiko, Oba Yuki, Kono Kei, Kinowaki Keiichi, Ohashi Kenichi, Wada Takehiko, Sawa Naoki, Ubara Yoshifumi
Аннотация
A 35-year-old woman was admitted for the examination of lower leg edema and proteinuria. A kidney biopsy showed membranous nephropathy (MN) with fine granular deposits of IgG along the glomerular capillary and poor spike formation, differing from primary MN in the presence of positive IgG3 and C1q. Lupus nephritis was excluded because serum complement and anti-dsDNA antibody, anti-Smith antibody, and anti-cardiolipin antibody tests were negative. The serological test for syphilis was positive, as was the Treponema pallidum hemagglutination test. The patient was diagnosed with syphilis, and the proteinuria disappeared with antibiotic treatment. In MN with positive IgG3 and C1q, syphilis nephropathy may be a differential diagnosis.