Journal of perinatology : official journal of the California Perinatal Association · 2026
Prediction of outcomes for premature infants referred to a quaternary NICU for respiratory escalation.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Sanabria Dafne, Dahash Basma, Natarajan Girija
Аннотация
OBJECTIVES: To identify predictors of death or tracheostomy in preterm infants referred to quaternary Neonatal Intensive Care Unit (NICU) for respiratory escalation at ≥34 weeks postmenstrual age (PMA).
METHODS: Single-center 13-year retrospective review of infants born <30 weeks gestation referred from Level III NICUs at ≥34 weeks PMA. Multivariable logistic regression identified independent predictors of death or tracheostomy.
RESULTS: Of 91 infants (mean GA 25.4 weeks), 48.4% reached the primary outcome; 15 died. Later PMA at admission and higher respiratory support were independent predictors of the primary outcome (AUC: 0.826; 95% CI 0.74-0.91). Redirection of care preceded 53% of deaths. At discharge, 86.8% of survivors required positive pressure or supplemental oxygen.
CONCLUSIONS: Nearly half of infants who had "late referrals" for respiratory escalation experienced death or tracheostomy. Admission PMA and ventilation mode provide prognostic value, facilitating timely multidisciplinary counseling and decision-making regarding long-term ventilatory support.
METHODS: Single-center 13-year retrospective review of infants born <30 weeks gestation referred from Level III NICUs at ≥34 weeks PMA. Multivariable logistic regression identified independent predictors of death or tracheostomy.
RESULTS: Of 91 infants (mean GA 25.4 weeks), 48.4% reached the primary outcome; 15 died. Later PMA at admission and higher respiratory support were independent predictors of the primary outcome (AUC: 0.826; 95% CI 0.74-0.91). Redirection of care preceded 53% of deaths. At discharge, 86.8% of survivors required positive pressure or supplemental oxygen.
CONCLUSIONS: Nearly half of infants who had "late referrals" for respiratory escalation experienced death or tracheostomy. Admission PMA and ventilation mode provide prognostic value, facilitating timely multidisciplinary counseling and decision-making regarding long-term ventilatory support.