Медицинская библиотека · Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] · 1999

[Application of cerium cytochemical method in observation of renal injury caused by oxygen free radical with cadmium induction].

Ye X, Sha J, Tang Y, Zheng Z, Yu B, Yang Y, Wu Y

Аннотация на английскомСтатьяПеревод в очереди

Аннотация

OBJECTIVE

To study acute renal injury caused by oxygen free radical with cadmium induction.

METHODS

Electron microscopy cytochemical and energy dispersive X-ray (EDX) analysis techniques were used.

RESULTS

Cadmium ions could enter the epithelial cells of renal proximal convoluted tubules. Excessive production of oxygen free radical was found in the kidney tissues, which located mainly in the endothelial cells of blood vessels, mitochondria of epithelial cells of renal proximal convoluted tubules, microvilli and basement membrane. Swelling of epithelial cells and mitochondria and drop of epithelial cells could occur in renal proximal convoluted tubules.

CONCLUSION

It suggests that cadmium ions can induce the formation of large amount of oxygen free radical and cause renal injury.

Для цитирования: Ye X, Sha J, Tang Y, Zheng Z, Yu B, Yang Y, Wu Y. [Application of cerium cytochemical method in observation of renal injury caused by oxygen free radical with cadmium induction].. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 1999.

Предметные рубрики MeSH

Acute Kidney Injury Animals Cadmium Cerium Electron Probe Microanalysis Free Radicals Histocytochemistry Hydrogen Peroxide Kidney Tubules, Proximal Male Oxygen Rats

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