Sirolimus-Induced Regression of Tuberous Sclerosis-Associated Cardiac Rhabdomyoma Causing Left Ventricular Outflow Tract Obstruction.

• Cardiac rhabdomyomas are closely associated with tuberous sclerosis. • Obstructive CRs historically have required surgery. • Use of mTOR inhibitors can cause regression and involution of CRs. • Use of mTOR inhibitors can reduce morbidity/mortality associated with cardiac surgery.