Trends in premature mortality and in years of life lost due to gastric cancer in Brazil's Central-West region.

The objective of this study was to analyze the rates and trends of premature mortality (30-69 years) and years of potential life lost (YPLL) due to gastric cancer in the capitals and other cities/towns of the Central-West region, from 1997 to 2021. This is an ecological time series study with data from the Mortality Information System. Premature mortality rates and YPLL were calculated and standardized by age. A joinpoint regression was used for trend. There was a predominance of premature deaths in males. The capitals of all states in the region had lower premature mortality rates compared to other cities/towns. A significant reduction in the trend of these rates was observed in all cities/towns of the region, except for women in the capital of Mato Grosso. The highest YPLL occurred among males, and the Federal District showed an increase of 1.27%. In general, premature mortality from gastric cancer showed significant declines in the Central-West region. Although the results are homogeneous across geographic units, prevention strategies, early diagnosis and increased access to oncological services are essential to reduce inequalities and improve prognoses.