Fertility and sterility · 2009
The significance of microsurgical varicocelectomy in the treatment of subclinical varicocele.
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Seo Ju Tae, Kim Kyung Tae, Moon Min Hoan, Kim Won Tae
Аннотация
OBJECTIVE: To assess the improvement of seminal characteristics and pregnancy rates after microsurgical varicocelectomy in men with subclinical varicocele.
DESIGN: Retrospective study.
SETTING: University infertility clinic.
PATIENT(S): One hundred forty-three patients with a subclinical left-sided varicocele.
INTERVENTION(S): Patients who agreed to microsurgical varicocelectomy (n = 25, surgery group), medical treatment with L-carnitine (n = 93 drug group), and those who did not agree to any treatment (n = 25, observation group) were enrolled.
MAIN OUTCOME MEASURE(S): Semen characteristics were reevaluated twice 6 months after treatment. The natural pregnancy rates were estimated by telephone interview between 1 and 2 years after treatment.
RESULT(S): In the surgery group, sperm counts improved significantly after microsurgical varicocelectomy. In the drug group, however, sperm parameters did not significantly improve after treatment. Natural pregnancy rates were 60.0% in the surgery group, 34.5% in the drug group, and 18.7% in the observation group. The natural pregnancy rate of the surgery group was higher than the other groups, and there were statistically significant differences among the three groups.
CONCLUSION(S): Surgical treatment is the best option for management of subclinical varicocele.
DESIGN: Retrospective study.
SETTING: University infertility clinic.
PATIENT(S): One hundred forty-three patients with a subclinical left-sided varicocele.
INTERVENTION(S): Patients who agreed to microsurgical varicocelectomy (n = 25, surgery group), medical treatment with L-carnitine (n = 93 drug group), and those who did not agree to any treatment (n = 25, observation group) were enrolled.
MAIN OUTCOME MEASURE(S): Semen characteristics were reevaluated twice 6 months after treatment. The natural pregnancy rates were estimated by telephone interview between 1 and 2 years after treatment.
RESULT(S): In the surgery group, sperm counts improved significantly after microsurgical varicocelectomy. In the drug group, however, sperm parameters did not significantly improve after treatment. Natural pregnancy rates were 60.0% in the surgery group, 34.5% in the drug group, and 18.7% in the observation group. The natural pregnancy rate of the surgery group was higher than the other groups, and there were statistically significant differences among the three groups.
CONCLUSION(S): Surgical treatment is the best option for management of subclinical varicocele.