Birthmarks of medical significance in the neonate.

Birthmarks are commonplace and most pose no significant detriment to health. It is usual for some 'birthmarks' to manifest within the first weeks to months of life and are not necessarily seen at birth. This is attributed in large part to the maturation of neonatal skin and the deepening of skin color over time. With time, increased pigment production in the skin by melanocytes eventually highlight the differences between normal and abnormal hypopigmented and hyperpigmented anomalies of the skin. Birthmarks can be seen as an isolated skin condition or serve as an important diagnostic aid for other more significant disorders. This review details four of the most common birthmarks regularly encountered in the neonatal period by perinatologists, obstetricians and pediatricians. This review emphasizes their medical significance and highlights any associated underlying systemic disease or genetic syndrome.