An Imidazo-Pyridin-Derived Fluorescent Probe for Monitoring Hydrogen Sulfide in Chinese Medicinal Materials.

Herein, an imidazo-pyridin-derived fluorescent probe ImPy-HS was developed for monitoring the hydrogen sulfide (H2S) level in the water decoction of Chinese medicinal materials. Under the excitation at 355 nm, ImPy-HS exhibited the obvious fluorescence response at 490 nm. The detection system with ImPy-HS showed the advantages including relatively high sensitivity, high selectivity, and high steadiness. Especially, in the water decoction of Chinese medicinal materials with H2S from both addition and excessive fumigation then reduction, ImPy-HS achieved the monitoring of the H2S level. ImPy-HS also realized the imaging of both exogenous and endogenous H2S as well as the water decoction-treated affection. The information here was meaningful for studying the quality control of Chinese medicinal materials.