The Journal of pediatrics · 2025
Resilience in Young Adults with Congenital Heart Disease in Relation to Neurodevelopment in the Preschool Period.
СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Kuni Tyler, Cianciulli Alana, Ittenbach Richard F, Combs Gabrielle, Randazzo Isabel, Licht Daniel J, Hampton Lyla, Gerdes Marsha, Bernbaum Judy, Gaynor J William, Burnham Nancy
Аннотация
OBJECTIVE: To determine if resilience among young adults with congenital heart disease is associated with patient characteristics and neurobehavioral status during the preschool period.
STUDY DESIGN: This study is a prospective, cross-sectional analysis of young adults enrolled in a longitudinal study of neurodevelopmental outcomes in congenital heart disease. All subjects underwent surgery with cardiopulmonary bypass at age ≤6 months of life. Resilience and general health status were evaluated using standardized questionnaires (RS-14 and SF-36, respectively). The relationships between resilience and patient and management factors as well as neurobehavioral status in the preschool period were examined.
RESULTS: The RS-14 and SF-36 were completed by 200 subjects (average age 20.1, IQR 19.2, 21.3 years). Median resilience score was 81.0 (CL0.95 78, 82), higher than the population average of 76.0 (P = .014). Higher resilience scores were correlated with higher health-related quality of life scores (r = 0.506, P < .001). Better executive function (P = .032) and social skills (P = .004) at the 4-year evaluation were associated with higher resilience in young adulthood. Inattention (P = .015) and pervasive development problems (P = .020) were inversely associated with resilience. No demographic, patient-related, or operative management factors were associated with higher or lower resilience (all P > .223).
CONCLUSIONS: Findings reported here show an association between preschool neurobehavioral status, overall health-related quality of life, and resilience in young adulthood. Identification of an at-risk population may provide an opportunity for intervention early in life, leading to improved psychosocial development with increased resilience.
STUDY DESIGN: This study is a prospective, cross-sectional analysis of young adults enrolled in a longitudinal study of neurodevelopmental outcomes in congenital heart disease. All subjects underwent surgery with cardiopulmonary bypass at age ≤6 months of life. Resilience and general health status were evaluated using standardized questionnaires (RS-14 and SF-36, respectively). The relationships between resilience and patient and management factors as well as neurobehavioral status in the preschool period were examined.
RESULTS: The RS-14 and SF-36 were completed by 200 subjects (average age 20.1, IQR 19.2, 21.3 years). Median resilience score was 81.0 (CL0.95 78, 82), higher than the population average of 76.0 (P = .014). Higher resilience scores were correlated with higher health-related quality of life scores (r = 0.506, P < .001). Better executive function (P = .032) and social skills (P = .004) at the 4-year evaluation were associated with higher resilience in young adulthood. Inattention (P = .015) and pervasive development problems (P = .020) were inversely associated with resilience. No demographic, patient-related, or operative management factors were associated with higher or lower resilience (all P > .223).
CONCLUSIONS: Findings reported here show an association between preschool neurobehavioral status, overall health-related quality of life, and resilience in young adulthood. Identification of an at-risk population may provide an opportunity for intervention early in life, leading to improved psychosocial development with increased resilience.