IEEE transactions on bio-medical engineering · 2026
Fusing Tabular Features and Deep Learning for Fetal Heart Rate Analysis: A Clinically Interpretable Model for Fetal Compromise Detection.
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Mendis Lochana, Karmakar Debjyoti, Palaniswami Marimuthu, Brownfoot Fiona, Keenan Emerson
Аннотация
OBJECTIVE: Cardiotocography (CTG) is commonly used to monitor fetal heart rate (FHR) and assess fetal well-being during labor. However, its effectiveness in reducing adverse outcomes remains limited due to low sensitivity and high false-positive rates. This study aims to develop an interpretable deep learning model that fuses FHR time series with tabular clinical features to improve prediction of fetal compromise (umbilical artery pH $< $ 7.05).
METHODS: We introduce Fusion ResNet, a novel architecture combining residual convolutional networks for FHR signal processing with a parallel neural network for tabular features. The model was trained and internally validated on a private dataset of 9,887 FHR recordings. External validation was performed on the open-access CTU-UHB dataset comprising 552 recordings. Model interpretability was evaluated using Shapley Additive Explanations (SHAP) and Gradient-Weighted Class Activation Mapping (Grad-CAM).
RESULTS: Fusion ResNet achieved a mean area under the ROC curve (AUC) of 0.77 during internal cross-validation and a state-of-the-art AUC of 0.84 on the CTU-UHB dataset, outperforming existing deep learning approaches. SHAP analysis identified key clinical features contributing to predictions, while Grad-CAM highlighted salient FHR patterns linked to fetal compromise.
CONCLUSION: The proposed model enhances predictive accuracy while providing clinically meaningful explanations, enabling more transparent and reliable CTG interpretation.
SIGNIFICANCE: This work demonstrates the potential of interpretable deep learning to improve fetal monitoring by integrating multimodal data, supporting timely and informed decision-making in obstetric care.
METHODS: We introduce Fusion ResNet, a novel architecture combining residual convolutional networks for FHR signal processing with a parallel neural network for tabular features. The model was trained and internally validated on a private dataset of 9,887 FHR recordings. External validation was performed on the open-access CTU-UHB dataset comprising 552 recordings. Model interpretability was evaluated using Shapley Additive Explanations (SHAP) and Gradient-Weighted Class Activation Mapping (Grad-CAM).
RESULTS: Fusion ResNet achieved a mean area under the ROC curve (AUC) of 0.77 during internal cross-validation and a state-of-the-art AUC of 0.84 on the CTU-UHB dataset, outperforming existing deep learning approaches. SHAP analysis identified key clinical features contributing to predictions, while Grad-CAM highlighted salient FHR patterns linked to fetal compromise.
CONCLUSION: The proposed model enhances predictive accuracy while providing clinically meaningful explanations, enabling more transparent and reliable CTG interpretation.
SIGNIFICANCE: This work demonstrates the potential of interpretable deep learning to improve fetal monitoring by integrating multimodal data, supporting timely and informed decision-making in obstetric care.