Nature communications · 2024
A deep-learning-based framework for identifying and localizing multiple abnormalities and assessing cardiomegaly in chest X-ray.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Fan Weijie, Yang Yi, Qi Jing, Zhang Qichuan, Liao Cuiwei, Wen Li, Wang Shuang, Wang Guangxian, Xia Yu, Wu Qihua, Fan Xiaotao, Chen Xingcai, He Mi, Xiao JingJing, Yang Liu, Liu Yun, Chen Jia, Wang Bing, Zhang Lei, Yang Liuqing, Gan Hui, Zhang Shushu, Liu Guofang, Ge Xiaodong, Cai Yuanqing, Zhao Gang, Zhang Xi, Xie Mingxun, Xu Huilin, Zhang Yi, Chen Jiao, Li Jun, Han Shuang, Mu Ke, Xiao Shilin, Xiong Tingwei, Nian Yongjian, Zhang Dong
Аннотация
Accurate identification and localization of multiple abnormalities are crucial steps in the interpretation of chest X-rays (CXRs); however, the lack of a large CXR dataset with bounding boxes severely constrains accurate localization research based on deep learning. We created a large CXR dataset named CXR-AL14, containing 165,988 CXRs and 253,844 bounding boxes. On the basis of this dataset, a deep-learning-based framework was developed to identify and localize 14 common abnormalities and calculate the cardiothoracic ratio (CTR) simultaneously. The mean average precision values obtained by the model for 14 abnormalities reached 0.572-0.631 with an intersection-over-union threshold of 0.5, and the intraclass correlation coefficient of the CTR algorithm exceeded 0.95 on the held-out, multicentre and prospective test datasets. This framework shows an excellent performance, good generalization ability and strong clinical applicability, which is superior to senior radiologists and suitable for routine clinical settings.