American journal of obstetrics and gynecology · 2001
Intracervical fibrin sealants: a potential treatment for early preterm premature rupture of the membranes.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Sciscione A C, Manley J S, Pollock M, Maas B, Shlossman P A, Mulla W, Lankiewicz M, Colmorgen G H
Аннотация
OBJECTIVE: We report our experience with a transvaginally applied intracervical fibrin sealant at <24 weeks' gestation.
STUDY DESIGN: This is an observational study of a referred patient population, with preterm premature rupture of the membranes at <24 weeks' gestation.
RESULTS: Twelve women consented to our protocol. The mean gestational age at preterm premature rupture of membranes was 19 weeks 4 days (range, 13-23 weeks); the mean gestational age at treatment was 20 weeks 5 days (range, 17-23 weeks). All women had a diminution in the amount of amniotic fluid leakage with an increase in amniotic fluid index. Among the 12 pregnancies (13 fetuses), there were 7 surviving neonates. Two women had apparent "resealing" of the membranes.
CONCLUSION: Fibrin sealants in midtrimester rupture of the membranes may lead to improved outcomes and now warrant formal evaluation.
STUDY DESIGN: This is an observational study of a referred patient population, with preterm premature rupture of the membranes at <24 weeks' gestation.
RESULTS: Twelve women consented to our protocol. The mean gestational age at preterm premature rupture of membranes was 19 weeks 4 days (range, 13-23 weeks); the mean gestational age at treatment was 20 weeks 5 days (range, 17-23 weeks). All women had a diminution in the amount of amniotic fluid leakage with an increase in amniotic fluid index. Among the 12 pregnancies (13 fetuses), there were 7 surviving neonates. Two women had apparent "resealing" of the membranes.
CONCLUSION: Fibrin sealants in midtrimester rupture of the membranes may lead to improved outcomes and now warrant formal evaluation.