International journal of surgery case reports · 2025
Malignant transformation of a mature teratoma in the duodenum: A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Phu Ly Huu, Vy Bui Thi Thuy, Binh Nguyen Viet, Bang Ho Tat, Tan Hoang Danh
Аннотация
INTRODUCTION: Mature teratomas of the duodenum are extremely rare, with only five cases reported in the English literature and none documented in Vietnam. Malignant transformation within a mature teratoma presents a challenging scenario for diagnosis and management, requiring a nuanced approach to treatment.
PRESENTATION OF CASE: We report the first documented case of malignant transformation in a duodenal mature teratoma in Vietnam. A 35-year-old male presented with persistent dull pain in the left flank, anorexia, and melena. Clinical examination revealed a palpable 10 × 14 cm mass in the left hypochondrium. Computed tomography (CT) imaging identified a tumor in the D4 segment of the duodenum with invasion into adjacent structures. The patient subsequently underwent surgical resection of the tumor, followed by adjuvant chemotherapy.
DISCUSSION: Histopathological analysis of the resected mass confirmed a moderately differentiated squamous cell carcinoma arising from a mature teratoma. Malignant transformations within teratomas, especially in such rare locations as the duodenum, require a multidisciplinary approach for optimal patient outcomes. In this case, the combination of surgical and adjuvant therapies was critical to managing the disease.
CONCLUSION: This case highlights the importance of early recognition and a multidisciplinary approach in managing malignant transformation in duodenal teratomas. The combination of surgery and adjuvant chemotherapy proved effective, with no recurrence or metastasis observed at five months follow-up.
PRESENTATION OF CASE: We report the first documented case of malignant transformation in a duodenal mature teratoma in Vietnam. A 35-year-old male presented with persistent dull pain in the left flank, anorexia, and melena. Clinical examination revealed a palpable 10 × 14 cm mass in the left hypochondrium. Computed tomography (CT) imaging identified a tumor in the D4 segment of the duodenum with invasion into adjacent structures. The patient subsequently underwent surgical resection of the tumor, followed by adjuvant chemotherapy.
DISCUSSION: Histopathological analysis of the resected mass confirmed a moderately differentiated squamous cell carcinoma arising from a mature teratoma. Malignant transformations within teratomas, especially in such rare locations as the duodenum, require a multidisciplinary approach for optimal patient outcomes. In this case, the combination of surgical and adjuvant therapies was critical to managing the disease.
CONCLUSION: This case highlights the importance of early recognition and a multidisciplinary approach in managing malignant transformation in duodenal teratomas. The combination of surgery and adjuvant chemotherapy proved effective, with no recurrence or metastasis observed at five months follow-up.