Incidence, predictors and outcomes of delirium in acute aortic syndrome.

OBJECTIVE: This study was undertaken to examine incidence and predictors of delirium in acute aortic syndrome (AAS) patients with or without surgery, and to evaluate its association with early and follow-up outcomes. METHODS: A cross-sectional study was retrospectively performed at a single center using a database that was prospectively maintained between 2019 and 2021. Measured outcomes included postoperative results and both early and follow-up survival rates. RESULTS: Five hundred ninety-two AAS patients were recruited. Delirium was seen in 31.6% (187/592) of patients. Predictors of delirium included the use of sedatives (odds ratio (OR) = 16.490, 95%-confidence interval (CI) = 8.981–30.279, P < 0.001) and sodium nitroprusside (OR = 2.676, 95%CI = 1.729–4.142, P < 0.001). Delirium was revealed as a risk factor for length of hospital stay (LOS) (OR = 1.101, 95%CI = 1.023–1.185, P < 0.05) and prolonged intensive care unit (ICU) stay (OR = 3.073, 95% CI = 1.744–5.415, P < 0.001). CONCLUSION: The incidence of delirium in AAS patients is 31.6%, significantly increasing LOS and ICU stay duration. The use of sedatives and sodium nitroprusside were revealed as risk factors for delirium.