Perforating Peripheral Ulcerative Keratitis in Syphilis.

PURPOSE: To present a case of peripheral ulcerative keratitis with perforation in the setting of syphilis.

METHOD: A single observational case report in urban USA.

CASE PRESENTATION: A patient with multiple sexual partners presented with bilateral peripheral ulcerative keratitis, unilateral corneal perforation, and a pustular rash. Workup was positive for syphilis as well as HSV, HIV, and multiple autoantibody tests. Findings improved after treatment for syphilis.

CONCLUSION

Bilateral peripheral ulcerative keratitis in syphilis has been reported in one prior case. However, corneal perforation in the setting of syphilis infection has not, to our knowledge, been reported previously.