The Pan African medical journal · 2019
Differential influence of race and environment on indeterminate reactivities to non-treponemal and treponemal antigens by immuno-chromatographic dual syphilis rapid test.
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Mbopi-Keou Francois-Xavier, Kalla Ginette Claude Mireille, Voundi Esther Voundi, Jenabian Mohammad-Ali, Mboumba Bouassa Ralph-Sydney, Talla Frédéric, Angwafo Fru F, Belec Laurent
Аннотация
INTRODUCTION: Syphilis rapid test results may be influenced by numerous environmental and genetic factors.
METHODS: The proportion of false positive syphilis non-treponemal (NT) and treponemal (T) test results using immuno-chromatographic dual syphilis rapid test on serum from Cameroonian blacks (n=103) versus French blacks (n=104) or French caucasians (n=51), all HIV-negative and free of clinical syphilis, was examined.
RESULTS: Black individuals in Cameroon had a significantly higher frequency of false positive NT or T tests than black individuals in France. black individuals in France had a higher frequency of indeterminate NT tests as compared to caucasians in France.
CONCLUSION: Both racial and environmental factors may affect immuno-chromatographic dual syphilis rapid testing.
METHODS: The proportion of false positive syphilis non-treponemal (NT) and treponemal (T) test results using immuno-chromatographic dual syphilis rapid test on serum from Cameroonian blacks (n=103) versus French blacks (n=104) or French caucasians (n=51), all HIV-negative and free of clinical syphilis, was examined.
RESULTS: Black individuals in Cameroon had a significantly higher frequency of false positive NT or T tests than black individuals in France. black individuals in France had a higher frequency of indeterminate NT tests as compared to caucasians in France.
CONCLUSION: Both racial and environmental factors may affect immuno-chromatographic dual syphilis rapid testing.