Visible-light-initiated metal-free Csp3 -Csp3 to Csp3 -N conversion in homobenzylic sulfonamides with N-iodoimides.

We report a simple protocol for the transformation of Csp3 -Csp3 to Csp3 -N in homobenzylic sulfonamides in combination with N-iodoimides to form gem-diamino derivatives. The reaction exhibits a wide functional group tolerance and allows the incorporation of bioactive-derived fragments. The mechanistic insights provided by control experiments and DFT calculations suggest that an imine intermediate is formed after C-C bond cleavage.