Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica · 2026
Therapeutic supplementation with antioxidants and vitamins improved sperm motility among infertile men with idiopathic low spermatogenesis.
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Sawaqed Fadi, Suoub Mohammed, Ayyad Malik, Al-Rawashdeh Samer, Al-Saraireh Yousef M, Salem Hareedy Mohammad
Аннотация
BACKGROUND: Spermatogenesis is worsened by reactive oxygen species (ROS) and antioxidants could reduce ROS induced sperm damage.
METHODS: This prospective cohort study evaluated the potential therapeutic effects of a combination of vitamins, minerals and antioxidants on the sperm quality parameters of infertile men with idiopathic low spermatogenesis. Seminal fluid analysis tests were performed before treatment, 3 and 6 months after treatment.
RESULTS: The treatment resulted in a significant improvement in the rate (%) of sperm motility from 16.95±6.93 to 23.11±8.87, after 3 months and reached 23.68±8.73 after 6 months (p=0.0006) whereas a non-significant increase in sperm count (from 13.05±8.1 to 15.79±7.9 after 3 months and 15.26±10.3 million/ml after 6 months (p=0.1650). Morphology and agglutination showed little changes. A positive correlation between sperm count and motility was observed after 3 months of treatment (r = 0.594; p=0.007).
CONCLUSIONS: The combination of vitamins and antioxidants improved the sperm motility significantly and to a lesser extent the sperm count, however, sperm morphology and agglutination remained relatively unchanged. Using antioxidants is safe and can improve semen parameters.
METHODS: This prospective cohort study evaluated the potential therapeutic effects of a combination of vitamins, minerals and antioxidants on the sperm quality parameters of infertile men with idiopathic low spermatogenesis. Seminal fluid analysis tests were performed before treatment, 3 and 6 months after treatment.
RESULTS: The treatment resulted in a significant improvement in the rate (%) of sperm motility from 16.95±6.93 to 23.11±8.87, after 3 months and reached 23.68±8.73 after 6 months (p=0.0006) whereas a non-significant increase in sperm count (from 13.05±8.1 to 15.79±7.9 after 3 months and 15.26±10.3 million/ml after 6 months (p=0.1650). Morphology and agglutination showed little changes. A positive correlation between sperm count and motility was observed after 3 months of treatment (r = 0.594; p=0.007).
CONCLUSIONS: The combination of vitamins and antioxidants improved the sperm motility significantly and to a lesser extent the sperm count, however, sperm morphology and agglutination remained relatively unchanged. Using antioxidants is safe and can improve semen parameters.