[The significance of use of anti-intrarenal artery spasm in renal allografts with HAR like manifestation].

In the past, severe ischemia of unknown cause in renal allografts after restoration of renal blood flow was regarded as a sign of hyperacute rejection (HAR) or other irreversible lesions, so that the grafts were usually excised during the operation. From January, 1994 to April, 1996, 8 cases of renal allografts with ischemia as described above were encountered in our hospital. Measures of anti-intrarenal artery spasm (IRAS) were taken to those grafts. Except that three grafts of HAR were excised, ischemia disappeared an renal functions recovered in 5 grafts. It suggested that ischemia of the five grafts was caused by IRAS. Thus, IRAS should be taken into account for renal allografts with severe ischemia of unknown cause and early anti-IRAS is essential for the diagnosis and treatment of IRAS.