[Preoperative preparation with plasmapheresis of patients with diffuse toxic goiter and intolerance to antithyroid drugs].

The authors analysed the results of therapy with plasmapheresis of 46 patients with diffuse toxic goiter showing intolerance to antithyroid therapy for the purpose of preoperative preparation. A therapeutic effect was achieved in 45 patients. Plasmapheresis resulted in the reduction of a period of preoperative preparation, the concentration of T4 and JgG, IgA and IgM decreased and the TTH level increased.