[Fetal examination of first trimester abortions].

INTRODUCTION

Rather few papers are about first trimesters pathology. The reason of this roots in the technical difficulties. The first trimesters pathology can not be separated from prenatal diagnostics.

OBJECTIVES

The authors summarized the molecular basis of embryology, malformations, and published cases that had been diagnosed prenatally.

MATERIALS AND

METHODS

In the I. Department of Obstetrics and Gynecology, Semmelweis University in Budapest between 1995. and 2000. altogether sixty embryos 70 gms or smaller were examined.

RESULTS

Malformations included neural tube defects, disorders of twinning, body stalk defect, chromosome aberrations, hydrops, omphalocele and gastroschisis.

CONCLUSIONS

Examination of early embryos may discover many results on the fields of prenatal diagnosis and the pathomechanism of developmental abnormalities.