[Experience in the use of vaginal and intracervical enzaprost suppositories in preparation for labor].

To improve the efficacy of prelabor treatment of pregnant women with some obstetrical abnormalities, such as over-term pregnancy, AB0- and Rh-isosensitization, anemia, gestosis of the second half of pregnancy, vaginal and intracervical suppositories containing 0.1 mg of enzaprost were administered to 102 women for 1-5 days. In 30 (29.4%) cases such treatment induced spontaneous labor. In 64 (62.7%) women labor was induced by deoxy-amino oxytocin, and in 8 (7.8%) women this latter drug had to be administered repeatedly to induce labor. The babies born to the women under observation had the Apgar score of 6-10, 92 (90.2%) of them had the score of 8-10. No stillbirths or early infant mortality cases were recorded. Therefore prelabor treatment with vaginal or intracervical suppositories with enzaprost is effective and safe for both mother and newborn.