Outcomes following endoscopic endonasal resection of craniopharyngiomas using intraoperative magnetic resonance imaging: Case series.

BACKGROUND

Craniopharyngiomas are rare tumors that originate from the squamous epithelium in Rathke's sac residues. There is a limited body of literature on the effect of using intraoperative magnetic resonance imaging (IO-MRI) in resection of craniopharyngiomas via endoscopic endonasal surgery (EES). The present study aims to assess the outcomes of EES for resection of craniopharyngiomas using IO-MRI.

METHODS

This is a retrospective analysis of the data collected on the point of care, consisting of 27 patients who underwent EES for histologically confirmed craniopharingiomas. All procedures were performed by a single neurosurgeon in between 2018 and 2020.

RESULTS

IO-MRI showed gross total resections were achieved in 25 (92.6 %) patients, and subtotal resections were achieved in 2 (7.4 %) patients. Pre-anticipated resection rate was achieved in the intraoperative scans in all patients and none of the patients required further resection. IO-MRI prolonged the anesthesia duration by an average of 32 ± 4 min. In the follow-up, 24 (88.9 %) cases of permanent diabetes insipidus and 10 (37 %) cases of panhypopituitarism were observed. Cerebrospinal fluid rhinorrhea complicated 6 (22.2 %) cases.

CONCLUSION

This present study is the largest study evaluating the efficiency of IO-MRI in craniopharyngioma. In addition, unlike other studies, only the patients who underwent EES were included. Although it has been known that the EES for craniopharyngioma is an effective and less invasive technique, this presented early results would suggest that combining this method with IO-MRI did not make significant contributions to surgical outcome.