Vulnerable newborn types: Analysis of population-based registries for 165 million births in 23 countries, 2000-2021.
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Suárez-Idueta Lorena, Yargawa Judith, Blencowe Hannah, Bradley Ellen, Okwaraji Yemisrach B, Pingray Veronica, Gibbons Luz, Gordon Adrienne, Warrilow Kara, Paixao Enny S, Falcão Ila Rocha, Lisonkova Sarka, Wen Qi, Mardones Francisco, Caulier-Cisterna Raúl, Velebil Petr, Jírová Jitka, Horváth-Puhó Erzsebet, Sørensen Henrik Toft, Sakkeus Luule, Abuladze Lili, Gissler Mika, Heidarzadeh Mohammad, Moradi-Lakeh Maziar, Yunis Khalid A, Al Bizri Ayah, Karalasingam Shamala D, Jeganathan Ravichandran, Barranco Arturo, Broeders Lisa, van Dijk Aimée E, Huicho Luis, Quezada-Pinedo Hugo Guillermo, Cajachagua-Torres Kim Nail, Alyafei Fawziya, AlQubaisi Mai, Cho Geum Joon, Kim Ho Yeon, Razaz Neda, Söderling Jonas, Smith Lucy K, Kurinczuk Jennifer, Lowry Estelle, Rowland Neil, Wood Rachael, Monteath Kirsten, Pereyra Isabel, Pravia Gabriella, Ohuma Eric O, Lawn Joy E, National Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group
Аннотация
DESIGN: Population-based, multi-country analysis.
SETTING: National data systems in 23 middle- and high-income countries.
POPULATION: Liveborn infants.
METHODS: Country teams with high-quality data were invited to be part of the Vulnerable Newborn Measurement Collaboration. We classified live births by six newborn types based on gestational age information (preterm <37 weeks versus term ≥37 weeks) and size for gestational age defined as small (SGA, <10th centile), appropriate (10th-90th centiles), or large (LGA, >90th centile) for gestational age, according to INTERGROWTH-21st standards. We considered small newborn types of any combination of preterm or SGA, and term + LGA was considered large. Time trends were analysed using 3-year moving averages for small and large types.
MAIN OUTCOME MEASURES: Prevalence of six newborn types.
RESULTS: We analysed 165 017 419 live births and the median prevalence of small types was 11.7% - highest in Malaysia (26%) and Qatar (15.7%). Overall, 18.1% of newborns were large (term + LGA) and was highest in Estonia 28.8% and Denmark 25.9%. Time trends of small and large infants were relatively stable in most countries.
CONCLUSIONS: The distribution of newborn types varies across the 23 middle- and high-income countries. Small newborn types were highest in west Asian countries and large types were highest in Europe. To better understand the global patterns of these novel newborn types, more information is needed, especially from low- and middle-income countries.