Clinical neuropharmacology · 2011
Treatment of psychogenic polydipsia with acetazolamide: a report of 5 cases.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Takagi Shunsuke, Watanabe Yutaka, Imaoka Takefumi, Sakata Masuhiro, Watanabe Masako
Аннотация
OBJECTIVE: Psychogenic polydipsia occurs frequently in patients with chronic psychiatric illness and is often unmanageable. We herein report 5 patients in whom acetazolamide was trialed for this symptom.
METHODS: We encountered a case in which polydipsia improved with incidental administration of acetazolamide. We then used this treatment for 4 additional cases of treatment-resistant psychogenic polydipsia, some of which were accompanied by hyponatremia.
RESULTS: Acetazolamide improved polydipsia and/or hyponatremia in 4 of the 5 cases. This treatment was well tolerated and allowed 3 of the patients to permanently leave isolation.
CONCLUSION: Acetazolamide appears to have a beneficial effect in psychogenic polydipsia.
METHODS: We encountered a case in which polydipsia improved with incidental administration of acetazolamide. We then used this treatment for 4 additional cases of treatment-resistant psychogenic polydipsia, some of which were accompanied by hyponatremia.
RESULTS: Acetazolamide improved polydipsia and/or hyponatremia in 4 of the 5 cases. This treatment was well tolerated and allowed 3 of the patients to permanently leave isolation.
CONCLUSION: Acetazolamide appears to have a beneficial effect in psychogenic polydipsia.