[Pseudoxanthoma elasticum associated with endocrine disorders, renal and adrenal cystic dysplasia, sensorineural hearing loss and mental disorders].

The paper reports a case of a 24-year old woman affected by pseudoxanthoma elasticum with typical flexural skin and ocular lesions. Other rarely associated diseases were also present: simple colloid goitre with hypothyroidism, renal and suprarenal capsules and ovarian cysts, consequent dysfunction of the pituitary-adrenal axis, hirsutism, cochlear hypoacusis, frontal sinus hypoplasia, and neuropsychiatric disorders. The association with hypothyroidism, hypoacusis and neuropsychiatric disorders is fully discussed, and it is suggested that the latter might be caused by peripheral vascular damage.