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DOI 10.1016/j.jaccas.2025.106654

Медицинская библиотека · JACC. Case reports · 2026

Transcatheter Closure of an LVOT to LA Fistula After Aortic Bioprosthetic Valve Fracture.

Sedhom Ramy, Mohammad Adeba, Alani Anas, Parwani Purvi, Sakr Antoine, Hoff Jason, Mohsen Amr

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Аннотация

BACKGROUND

Left ventricular outflow tract to left atrium (LVOT-LA) fistula is an uncommon but serious complication of transcatheter aortic valve replacement (TAVR), associated with adverse clinical outcomes.

CASE SUMMARY: A 78-year-old man with a history of surgical aortic valve replacement, followed by valve-in-valve TAVR, presented with significant dyspnea thought to be due to a valve-in-valve patient prosthesis mismatch. He underwent valve fracture of the TAVR valve. Post-balloon valvuloplasty, the patient developed an LVOT-LA fistula. He presented with worsening exertional dyspnea. Transesophageal echocardiography confirmed the fistula, and a percutaneous transvenous closure using an Amplatzer IV vascular plug was successfully performed. After the procedure, the patient's symptoms markedly improved.

DISCUSSION: Percutaneous closure of an LVOT-LA fistula is technically feasible when performed in experienced centers. Small, low-profile occlusion devices, such as the Amplatzer IV vascular plug, are preferred to minimize the risk of interference with adjacent valvar structures.

TAKE-HOME MESSAGES: Intracardiac shunts are uncommon but serious complications of TAVR. Percutaneous closure is technically feasible when performed at experienced centers.

Для цитирования: Sedhom Ramy, Mohammad Adeba, Alani Anas, Parwani Purvi, Sakr Antoine, Hoff Jason, Mohsen Amr. Transcatheter Closure of an LVOT to LA Fistula After Aortic Bioprosthetic Valve Fracture.. JACC. Case reports. 2026. DOI: 10.1016/j.jaccas.2025.106654.
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