Chemistry & biodiversity · 2022
Chemical Composition Determination and Evaluation of the Antimicrobial Activity of Essential Oil from Croton blanchetianus (Euphorbiaceae) against Clinically Relevant Bacteria.
СтатьяНазвание и аннотация: Перевод в очереди
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Nunes Aluska Kelly A, Araújo Malveira Ellen, Lopes Andrade Alexandre, Barbosa da Silva Wildson Max, de Morais Selene Maia, Silva Dos Santos Hélcio, Cavalcanti de Albuquerque Cynthia, Holanda Teixeira Edson, do Nascimento Souza Diego Nathan, Alves de Vasconcelos Mayron
Аннотация
In this study, the chemical composition of the essential oil (EO) extracted from Croton blanchetianus Baill leaves was identified, and antimicrobial and antibiofilm activities against Staphylococcus aureus, Staphylococcus epidermidis, and Escherichia coli strains were determined. Moreover, the effects of EO in combination with ampicillin and tetracycline were investigated. Thirty-four components, mainly mono-and sesquiterpenes that represented 94.05 % of the chemical composition, were identified in the EO. The EO showed bacteriostatic and bactericidal activities against all strains tested. Furthermore, the EO showed a synergistic effect with ampicillin and tetracycline. EO significantly inhibited biofilm formation and reduced the number of viable cells in biofilms. The EO may be a promising natural product for preventing bacterial biofilm infections.