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DOI 10.3390/ijms26188878

Медицинская библиотека · International journal of molecular sciences · 2025

Understanding Endometriosis: A Broad Review of Its Causes, Management, and Impact.

Czubak Paweł, Herda Karolina, Niewiadomska Iwona, Putowski Lechosław, Łańcut Mirosław, Masłyk Maciej

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Аннотация

Endometriosis is a complex gynecological condition affecting 10% of women globally, characterized by the growth of endometrial-like tissue outside the uterus, leading to chronic pelvic pain, infertility, reduced quality of life, and a risk of cancer. This review examines the multifaceted aspects of endometriosis, including its causes, diagnostic approaches, and management strategies. Genetic and environmental factors, hormonal influences, and immunological dysregulation are addressed as potential drivers of disease progression. Treatment options, including pharmacological interventions (hormone therapy, pain management) and surgical interventions, are assessed for their effectiveness in alleviating symptoms and improving outcomes. Emerging therapies, such as small-molecule inhibitors and anti-angiogenic agents, are also explored. Additionally, the psychological impact of endometriosis is addressed, emphasizing the need for holistic care. This review highlights the importance of continued research to unravel the precise mechanisms underlying endometriosis and to develop targeted therapies for improved patient care.

Для цитирования: Czubak Paweł, Herda Karolina, Niewiadomska Iwona, Putowski Lechosław, Łańcut Mirosław, Masłyk Maciej. Understanding Endometriosis: A Broad Review of Its Causes, Management, and Impact.. International journal of molecular sciences. 2025. DOI: 10.3390/ijms26188878.

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