Akusherstvo i ginekologiia · 2011
[Some aspects of prostaglandin administration in obstetrics: preliminary report].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Marinov B, Andreeva A, Cankova M
Аннотация
UNLABELLED: Prostaglandin preparations are widely used in the OB-GYN practice today. This is due to their high efficiency and their potency to prevent a surgical intervention and serious complications. The aim of this study is to share our experience in the prevention of hypo- and atonic, itra- and postoperative hemorrhage after Caesarian Section on multiple pregnancy.
MATERIALS AND METHODS: 31 patients with multiple pregnancy for the period of Jan 2010 to June 2011, delivered by Cesarean Section due to unfavorable fetus presentation. Time of delivery- 34 to 38 weeks of gestation. 13 of them represented our work group, amongst them 11 with twin pregnancy and 2 with triplets. They were administered, in theatre, prostaglandin F2alpha as 1 ampule of Prostin 15M (Carboprost tromethamole 0.25 mg) in the uterus wall, as a prophylaxis. The control group consisted of 18 multiple pregnancy patients, chosen randomly and delivered again by C.S., 14 of them with twin pregnancy and 4 with triplets.
RESULTS: In our work group the average maternal blood loss was 520 ml +/- 104 ml, compared to 760 +/- 80 ml in the control group. There were patients in the control group with average blood loss of 1500 ml leading to the need of urgent and lifesaving measures.
CONCLUSIONS: Nevertheless the small number of cases we had, we dare to say the administration of Carboprost tromethamole - Prostin 15M, intramurally in the uterus during Cesarean section on multiple pregnancy, diminishes the risk of severe hypo- and atonic hemorrhage in theatre and postpartum.
MATERIALS AND METHODS: 31 patients with multiple pregnancy for the period of Jan 2010 to June 2011, delivered by Cesarean Section due to unfavorable fetus presentation. Time of delivery- 34 to 38 weeks of gestation. 13 of them represented our work group, amongst them 11 with twin pregnancy and 2 with triplets. They were administered, in theatre, prostaglandin F2alpha as 1 ampule of Prostin 15M (Carboprost tromethamole 0.25 mg) in the uterus wall, as a prophylaxis. The control group consisted of 18 multiple pregnancy patients, chosen randomly and delivered again by C.S., 14 of them with twin pregnancy and 4 with triplets.
RESULTS: In our work group the average maternal blood loss was 520 ml +/- 104 ml, compared to 760 +/- 80 ml in the control group. There were patients in the control group with average blood loss of 1500 ml leading to the need of urgent and lifesaving measures.
CONCLUSIONS: Nevertheless the small number of cases we had, we dare to say the administration of Carboprost tromethamole - Prostin 15M, intramurally in the uterus during Cesarean section on multiple pregnancy, diminishes the risk of severe hypo- and atonic hemorrhage in theatre and postpartum.