[Problems of pathomorphology of generalized Sanarelli-Shwartzman phenomenon in endotoxic shock].

On the basis of 52 sectional observation on post-delivery and post-abortion complications the clinico-morphological picture of endotoxin shock, which proceeded according to the type of the generalized phenomenon of Sanarelli-Schwartzmann, is discussed. The condition was characterized by an acute onset, signs of shock with a drop of arterial pressure, the hemorrhagic syndrome. Morphologically, disorder of the microcirculation was observed: hyperemia, stases in many organs, disseminated microthrombosis in capillaries. The thrombosis was complicated by origination of necroses of the adrenal cortex and adrenals, hypophysis, by ulcers in the stomach and intestine. The "coagulopathy of consumption" was the cause of appearing multiple hemorrhages and bleedings.