Diabetes mellitus in a 6-month-old Charolais heifer calf.

This unthrifty heifer calf was thin, weak and had a dull haircoat. Urinalysis and blood work revealed glycosuria, ketonuria, hypoproteinemia, and hyperglycemia. Euthanasia and necropsy were performed, revealing multifocal intersitial lymphocytic infiltration, an absence of islet cells, and a positive stain for bovine viral diarrhea virus in the pancreas.