Factors associated with the development of spontaneous intertwin membrane separation in dichorionic twin pregnancy.

OBJECTIVE

We examined factors associated with the development of spontaneous intertwin membrane separation in dichorionic twin pregnancy.

METHODS

Medical charts of 618 dichorionic twin pregnancies without the history of amniocentesis managed after 22 weeks' gestation at Japanese Red Cross Katsushika Maternity Hospital between 2002 and 2017 were reviewed.

RESULTS

Twenty-four cases (3.9%) were diagnosed with spontaneous intertwine membrane separation. The presence of different fetal sex and separated placentae were associated with the development of spontaneous intertwin membrane separation in dichorionic twin pregnancy (different fetal sex: crude odds ratio 2.44, 95% confidence interval, 1.1-5.5, p = .03; separated placentae: crude odds ratio 4.14, 95% confidence interval, 1.3-13, p = .01).

CONCLUSION

The development of spontaneous intertwin membrane separation in dichorionic twin pregnancies seemed to be associated with dizygotic.