The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023
Preliminary Development of an MRI Atlas for Application to Cleft Care: Findings and Future Recommendations.
СтатьяМногоцентровое исследованиеПоддержка NIH: внешняя программаНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Perry Jamie L, Gilbert Imani R, Xing Fangxu, Jin Riwei, Kuehn David P, Shosted Ryan K, Woo Jonghye, Liang Zhi-Pei, Sutton Bradley P
Аннотация
OBJECTIVE: To introduce a highly innovative imaging method to study the complex velopharyngeal (VP) system and introduce the potential future clinical applications of a VP atlas in cleft care.
DESIGN: Four healthy adults participated in a 20-min dynamic magnetic resonance imaging scan that included a high-resolution T2-weighted turbo-spin-echo 3D structural scan and five custom dynamic speech imaging scans. Subjects repeated a variety of phrases when in the scanner as real-time audio was captured.
SETTING: Multisite institution and clinical setting.
PARTICIPANTS: Four adult subjects with normal anatomy were recruited for this study.
MAIN OUTCOME: Establishment of 4-D atlas constructed from dynamic VP MRI data.
RESULTS: Three-dimensional dynamic magnetic resonance imaging was successfully used to obtain high quality dynamic speech scans in an adult population. Scans were able to be re-sliced in various imaging planes. Subject-specific MR data were then reconstructed and time-aligned to create a velopharyngeal atlas representing the averaged physiological movements across the four subjects.
CONCLUSIONS: The current preliminary study examined the feasibility of developing a VP atlas for potential clinical applications in cleft care. Our results indicate excellent potential for the development and use of a VP atlas for assessing VP physiology during speech.
DESIGN: Four healthy adults participated in a 20-min dynamic magnetic resonance imaging scan that included a high-resolution T2-weighted turbo-spin-echo 3D structural scan and five custom dynamic speech imaging scans. Subjects repeated a variety of phrases when in the scanner as real-time audio was captured.
SETTING: Multisite institution and clinical setting.
PARTICIPANTS: Four adult subjects with normal anatomy were recruited for this study.
MAIN OUTCOME: Establishment of 4-D atlas constructed from dynamic VP MRI data.
RESULTS: Three-dimensional dynamic magnetic resonance imaging was successfully used to obtain high quality dynamic speech scans in an adult population. Scans were able to be re-sliced in various imaging planes. Subject-specific MR data were then reconstructed and time-aligned to create a velopharyngeal atlas representing the averaged physiological movements across the four subjects.
CONCLUSIONS: The current preliminary study examined the feasibility of developing a VP atlas for potential clinical applications in cleft care. Our results indicate excellent potential for the development and use of a VP atlas for assessing VP physiology during speech.