The journal of sexual medicine · 2010
Karyotyping, is it worthwhile in transsexualism?
СтатьяНазвание и аннотация: Перевод в очереди
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Inoubli Adrien, De Cuypere Griet, Rubens Robert, Heylens Gunter, Elaut Els, Van Caenegem Eva, Menten Björn, T'Sjoen Guy
Аннотация
INTRODUCTION: Karyotyping is often performed in transsexual individuals.
AIM: Quantification and characterization of karyotype findings and abnormalities in transsexual persons.
MAIN OUTCOME MEASURES: Karyotypes were listed both in male-to-female and in female-to-male transsexual persons.
METHODS: The data were collected through a retrospective study.
RESULTS: Karyotypes of 368 transsexual individuals (251 male-to-female, 117 female-to-male) are described. Normal findings were found in 97.55%. Prevalence of abnormal karyotypes was 3.19% among male-to-female, and 0.85% among female-to-male transsexuals. Nine karyotypes showed variations; Klinefelter syndrome was confirmed in three persons, whereas others displayed autosomal aberrations.
CONCLUSION: Karyotyping is only of very limited information in the transsexual population.
AIM: Quantification and characterization of karyotype findings and abnormalities in transsexual persons.
MAIN OUTCOME MEASURES: Karyotypes were listed both in male-to-female and in female-to-male transsexual persons.
METHODS: The data were collected through a retrospective study.
RESULTS: Karyotypes of 368 transsexual individuals (251 male-to-female, 117 female-to-male) are described. Normal findings were found in 97.55%. Prevalence of abnormal karyotypes was 3.19% among male-to-female, and 0.85% among female-to-male transsexuals. Nine karyotypes showed variations; Klinefelter syndrome was confirmed in three persons, whereas others displayed autosomal aberrations.
CONCLUSION: Karyotyping is only of very limited information in the transsexual population.