A psychometric approach to the relationship between hand-foot preference and auditory hallucinations in the general population: atypical cerebral lateralization may cause an abnormal sense of agency.

The present study examined the relationship between the atypical cerebral lateralization pattern represented in hand and foot preferences and schizotypal personality traits, especially proneness to auditory hallucinations as related to a sense of agency. A sense of agency, measured with questionnaires in the present study, is the sense that "I am the one who causes the actions." Although atypical lateralization and an abnormal sense of agency may be related to schizophrenia or schizotypal personality, the connection between them has remained unclear. The present study used cluster analysis to categorize the handedness-footedness combinations. The results indicated that people with right-handedness and left-footedness may have more schizotypal traits and that their abnormal sense of agency may cause schizotypal personality traits. Although the reasons for crossed lateral preference remain unclear, we discuss this in terms of early switching in handedness, which may underlie atypical lateralization and lead to the experience of auditory hallucinations deriving from an abnormal sense of agency.