General hospital psychiatry · 2012
The effects of memantine on a patient having preclinical dementia with Lewy bodies.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Takaya Masahiko, Matsusaka Kazuyo, Yanagida Makoto, Kimura Ryo, Matsunaga Hidenori
Аннотация
OBJECTIVE: Memantine has been reported to have positive effects on visual hallucinations and cognition in patients with dementia with Lewy bodies (DLB). We hypothesized that memantine would have similar effects on a patient having Charles Bonnet syndrome, preclinical DLB.
METHOD: We evaluated the effect of memantine on visual hallucination, cognitive abilities and so on from baseline to 4 months after the start of medication.
RESULTS: Treatment of the patient with memantine resulted in the disappearance of visual hallucinations but could not stop the progression to dementia.
CONCLUSIONS: Our results suggested that, for a patient having preclinical DLB, memantine had some degree of positive effects, but the mechanism remains to be revealed.
METHOD: We evaluated the effect of memantine on visual hallucination, cognitive abilities and so on from baseline to 4 months after the start of medication.
RESULTS: Treatment of the patient with memantine resulted in the disappearance of visual hallucinations but could not stop the progression to dementia.
CONCLUSIONS: Our results suggested that, for a patient having preclinical DLB, memantine had some degree of positive effects, but the mechanism remains to be revealed.