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DOI 10.3233/thc-231864

Медицинская библиотека · Technology and health care : official journal of the European Society for Engineering and Medicine · 2024

Systematic quantitative evaluation of gene polymorphism and therapeutic effect of xingnaojing injection in patients with brain injury.

Yu Limei, Wang Yuxia, Chen Yun, Wang Yakun, Zhang Haida, Zhang Meiqi, Li Chen

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Аннотация

BACKGROUND

The incidence of brain injury is increasing year by year, and it has become one of the major diseases threatening human life in today's society. From the perspective of the causes of brain injury, it is mainly due to falls from high places, traffic accidents, etc. Severe brain injury patients often lose consciousness. In recent years, the emergence of integrated traditional Chinese and Western medicine has provided a new approach and new ideas for the treatment of craniocerebral trauma.

OBJECTIVE

The article systematically and scientifically expounded the role of Xingnaojing injection in the treatment of brain injury by comparing the GCS (Glasgow Coma Scale) score, changes in intracranial pressure, the incidence of complications after brain injury, the transformation from moderate brain injury to severe brain injury, and recovery of consciousness.

METHODS

For the problem of gene polymorphism in patients with brain injury, this article discussed the role of APOE2 (Apolipoprotein E2), ε3, ε4 in brain injury. All patients had a clear history of trauma and received strict nervous system examination and CT scanning when they were admitted to the hospital. After craniocerebral trauma surgery or conservative therapy, patients should take a Xingnaojing injection of 30 ml and a 0.9% sodium chloride injection of 250 ml after admission. After the operation, respiratory tract nursing should be strengthened, and patients who cannot eat should be given nasal feeding, acupuncture, and physiotherapy to prevent bedridden complications.

RESULTS

The probability of epilepsy after brain injury was 27%.

CONCLUSION

The article would help to evaluate the degree of brain damage and prognosis of patients.

Для цитирования: Yu Limei, Wang Yuxia, Chen Yun, Wang Yakun, Zhang Haida, Zhang Meiqi, Li Chen. Systematic quantitative evaluation of gene polymorphism and therapeutic effect of xingnaojing injection in patients with brain injury.. Technology and health care : official journal of the European Society for Engineering and Medicine. 2024. DOI: 10.3233/thc-231864.

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