Characterization of a cDNA encoding the precursor of platelet aggregation inhibition and metalloproteinase from Trimeresurus mucrosquamatus venom.

This paper presents the nucleotide sequence of a cDNA encoding a full-length precursor of a novel platelet aggregation inhibitor named trimucrin and a hemorrhagic metalloproteinase from Trimeresurus mucrosquamatus snake venom. The deduced structure of the precursor protein is compared with those of other members of the metalloproteinase/disintegrin family.