Estimating the economic burden of Parkinson's disease in China, 2020-2040: a projection and health-augmented macroeconomic modelling study.

Parkinson's disease (PD) is a growing global health concern. The goal of this research is to estimate the financial impact of PD in 31 provinces in the mainland of China from 2020 to 2040. The study gathered several datasets including China Statistical Yearbook, China Labor Statistical Yearbook, China Health Statistical Yearbook, and the Global Burden of Disease study 2023. We leveraged a health-augmented macroeconomic model to calculate the provincial economic toll of PD, taking into consideration the direct and indirect effects of PD-related deaths and illness on labor supply, and variations in educational background and work experience by sex and age. PD is expected to cause a substantial economic burden from 2020 to 2040, amounting to 473 billion Chinese yuan (CNY), which is 0.017% of the gross domestic product. The burden is highest in Jiangsu, Guangdong, and Shandong Provinces, whereas the burden proportion in the provincial gross domestic product is highest in Heilongjiang at 0.029%, and the economic burden per capita is highest in Shanghai at 868 CNY. A strong positive correlation between disability-adjusted life years and economic burden is found (Pearson correlation coefficient = 0.871, P-value < 0.001). These findings demonstrate the need for more specific regional health policies in line with the long-term care, diagnosis, and treatment for PD across China.