The American journal of drug and alcohol abuse · 2008
Electrophoretic profile of serum proteins in opium and heroin dependents.
Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Divsalar Kouros, Meymandi Manzumeh Shamsi, Saravani Ramin, Zarandi Minoo Mahmoudi, Shaikh-Al-Eslami Azar
Аннотация
OBJECTIVES: In this cross-sectional case-control study, albumin and globulin profile in the serum of opium and heroine addicts have been compared with correspondent values in a matched control group.
METHODS: Opioid consumption was confirmed by laboratory diagnostic tests on urine samples and protein electrophoresis of serum was performed to determine the concentration and profile of serum proteins.
RESULTS: There was no significant difference in albumin, alpha(1)-globulin, alpha(2)-globulin, and beta-globulin concentration among groups. Gamma-globulin concentration in opium and heroin addicts showed no significant difference, but it was significantly lower in comparison to the control group.
CONCLUSION: This finding may be attributed to the higher probability of infectious diseases in opioids addicts.
METHODS: Opioid consumption was confirmed by laboratory diagnostic tests on urine samples and protein electrophoresis of serum was performed to determine the concentration and profile of serum proteins.
RESULTS: There was no significant difference in albumin, alpha(1)-globulin, alpha(2)-globulin, and beta-globulin concentration among groups. Gamma-globulin concentration in opium and heroin addicts showed no significant difference, but it was significantly lower in comparison to the control group.
CONCLUSION: This finding may be attributed to the higher probability of infectious diseases in opioids addicts.