Pain medicine case reports · 2026
Therapeutic Effect of Suzetrigine in the Management of Notalgia Paresthetica: A Case Report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lee Brian, Wang Wendy, Cha Denny, Lin Jeffrey
Аннотация
BACKGROUND: Notalgia paresthetica is a sensory neuropathy characterized by severe pruritus, pain, and hyperpigmented patches in the T2-T6 distribution. Despite multiple treatment options, there are no established guidelines to manage this challenging sensory neuropathy.
CASE REPORT: A 64-year-old man presented to the pain clinic with persistent notalgia paresthetica for 5 years. He was unable to tolerate oral neuropathic agents, and insurance coverage for capsaicin cream and botulinum toxin injections was denied. He was treated with suzetrigine, a novel NaV1.8 channel inhibitor, for 1 month and experienced complete resolution of symptoms.
CONCLUSIONS: The etiology of notalgia paresthetica has not been fully elucidated, but it is thought to involve irritation and aberrant firing of the thoracic spinal nerves.
UNLABELLED: This response to suzetrigine suggests that it may act as a peripheral nerve membrane stabilizer and may be a treatment option for this condition.
CASE REPORT: A 64-year-old man presented to the pain clinic with persistent notalgia paresthetica for 5 years. He was unable to tolerate oral neuropathic agents, and insurance coverage for capsaicin cream and botulinum toxin injections was denied. He was treated with suzetrigine, a novel NaV1.8 channel inhibitor, for 1 month and experienced complete resolution of symptoms.
CONCLUSIONS: The etiology of notalgia paresthetica has not been fully elucidated, but it is thought to involve irritation and aberrant firing of the thoracic spinal nerves.
UNLABELLED: This response to suzetrigine suggests that it may act as a peripheral nerve membrane stabilizer and may be a treatment option for this condition.